Identification and characterization of factors affecting cytoskeletal proteins--the mediators of bacterial cell shape

Premature aging and muscular dystrophy have been linked to disorders in the Lamin A/C intermediate filaments (IF). Little is understood about what regulates IFs in human cells. An intermediate-like filament with domains similar to Lamin A/C has recently been identified in an aquatic bacterium Caulobacter crescentus. This intermediate-like filament confers a crescent shape to C....